WELCOME TO
General Biochemistry
Summer 2016
Class Times - MWF 1:15 to 2:20PM PG6-116
(Parking Garage-6) .
Principles of STUDY
How to Prepare for Class
|
Instructor |
Email |
Phone |
Office hours |
|
John
Makemson |
makemson@fiu.edu |
305-348-3097 |
OE
246/247: MWF Mornings after 11AM + Afternoons before 4PM |
Learning
Biochemistry
Catalog
Description:
Chemistry of proteins, lipids, carbohydrates, and nucleic acids;
principles of enzymology, metabolism and bioenergetics.
Student's Learning Objectives: Students will know the chemical
structures and chemistry of biological polymers (proteins,
carbohydrates, lipids and nucleic acids) and their monomers (amino
acids, sugars, fatty acids and other lipid monomers, and nucleotides) as well
as the roles of these biological molecules in living cells. Students
will be able to solve amino acid sequences of protein, nucleotide
sequences of nucleic acids from experimental data and how to determine
structures of carbohydrates and lipids. Students will be able
analyze enzyme kinetic data as well as the bioenergetics/thermodynamics
of biochemical reactions. Students will know the reactions of major
metabolic pathways: Central Metabolism (Glycolysis-Gluconeogenesis, Pentosephosphate Patthway, Citric
Acid Cycle) and Respiratory Electron Transport System, Glyoxylate
Cycle; Beta-oxidation of fatty acids and be able to analyze the regulation
of these pathways.
Lecture Format: Narrated PowerPoints are in MP4 format that can be
viewed on standard and laptop computers as well as tablets. These were
made using the continually updated PowerPoints from the instructor's regular
lectures. They usually last less than a full lecture (most are 30-40 min)
because there is no interaction with an audience. A few
"lectures" go longer than an hour, but each of these are used for two
class periods. Each "lecture" is at a private YouTube site and the
FIU Media Site. Please use the one that works best for you. The
links to the lectures are below in the schedule.
THE FLIPPED CLASS: the lectures here are narrated
PowerPoints that you can view at any time you choose before class. The
Power Points used in lecture can also be downloaded to take notes on if you
convert them to pdf and print them out. It is to your distinct advantage
to have the lecture pdf printed out so when you are viewing the narrated
PowerPoint because you can pause the narrated PowerPoint and take notes on the
pdf. If you went too slow, you can always back the lecture up and get to
what you missed. In other words: YOU HAVE TOTAL CONTROL of the LECTURE. This
makes learning paced to your ability to ACTIVELY LEARN. PLEASE DO NOT
JUST LISTEN, but rather STUDY the LECTURE BEFORE CLASS. Further, you can go to
the "lecture" as many times as you like. Please do the selected
End of Chapter problems before class: in class we will work on problems
like these and Case Studies. Doing them before class will pay off in
higher Clicker grades.
ADVANTAGES OF THE FLIPPED CLASS: Because each class is an active learning experience,
students have performed much better on the Exams, usually 10 to 20% better than
those using traditional lecture format. This ONLY WORKS for students that
STUDY BEFORE CLASS. The payoff is student problem solving and critical thinking
skills improve. This has a distinct advantage when taking admission exams
for graduate schools (GRE) and any of those for health professions (MCAT, DAT,
etc.).
FREE STUFF: A Biochemistry MOOC (massive on-line open course):
oli.cmu.edu/courses/free-open/biochemistry-course-details. This course
was created at Carnegie-Mellon University. It is free and you can use it as an
additional resource. It has a slightly different structure, but also has problem
sets for each chapter. Further there is a free e-textbook by Kevin Ahern
(Oregon State University): BIOCHEMISTRY FREE AND EASY (you can download from
various sources, the Kindle version is also free from Amazon, particularly good
if you like songs about molecules) and Kevin Aherns
lectures are free and on YouTube.
Each
Class Time has a Graded Component that REQUIRES you to
have a working iClicker for Each Class. Classroom
work counts for 1/3rd of your grade. Last semesters, the i-Clicker-Go
app had wi-fi connection problems; the safest is the
basic iClicker. New and Used iClickers are available from the Bookstore. But you might
get better deals elsewhere. THE MOST IMPORTANT
POINT: Get your iClicker REGISTERED to YOUR NAME as
it appears in PantherSoft. If you have
a multi-word last name such as "de la Vega", it has to be registered
with underlines as "de_la_Vega" which makes
it look like one word at the iClicker database. This
is the only way it will add your clicker points into the gradebook. We will be
testing your iClicker response during the first week
with non-graded material.
Graded
iClicker responses begin the 2nd week
Prerequisites : General Biology - BSC 1010
& BSC 1011 and Organic Chemistry - CHM 2210 & CHM 2211 all with grades
of C or Better.
Text: Principles
of Biochemistry,
Lehninger, Sixth Edition (Nov. 2013) -
Available in Three Different Formats: Hardbound Text
Loose-leaf Text
(10:1-4641-1-1064-6, 13:978-1-461-1) , and e-book. The latter two cost
significantly less than the Hardbound Text. The loose-leaf form (you
don't have to carry the whole thing around each week) was ordered for the
Bookstore. The e-book is at: http://ebooks.bfwpub.com/lehninger6e
or at http://www.Chegg.com (which also has rental books).
New
and used copies (of the 6th Edition) of the textbook are available at the FIU
Bookstore in the Graham Center. The bookstore sells them at highest possible
price. You can save by using the web: new and used are discounted at
half.com, abebooks.com, and Amazon. Also check ebay.
International editions are at about half the price: check out
amazaon.co.uk and others. The international editions are usually paper back,
but otherwise are identical to the very costly book in the bookstore (probably
~$280). Be careful about ordering the text and not the study guide. You
do not need the study guide: Answers to all of the End of Chapter
Problems are in the end of the text; and Solutions to the End of Chapter
Problems are Present as Word or pdf files from this syllabus.
Tentative
Syllabus
See Below About
Practice Exams
|
May |
PowerPoint of
"Lecture" Download and Convert to pdf to Use as
Notes When Doing the Narrated Power Point Lecture. |
Narrated
Power Point "Lecture" KNOW WELL, BEFORE CLASS |
DO THESE BEFORE CLASS: End Of Chapter Problems to
Solve. Solutions to the Selected EOC Problems are in Word format. Abbreviated
Solutions following page 1198 in the textbook: Best Source! |
|
16
M |
YouTube FIU Media Site |
||
|
18W |
1, 3, 5, 8, 11, 12 Ch01SelectedSolutions |
||
|
20
F |
1-5, 8, 11-18, 20, 26 Ch02SelectedSolutions |
||
|
23 M |
|||
|
25 W |
8-11, 13, 15, 16 Ch03Pt-2 Selected Solutions |
||
|
27 F |
18, 19, 21, 22 Ch03Pt-3 Selected Solutions |
||
|
30
M |
Memorial Day Holiday |
|
|
|
June |
|
|
|
|
1 W |
EXAM 1 A through F in Pg6-116, G though Z in RDB-1100 (Law College) |
|
50 points. Please bring a calculator
(non-graphing). This exam integrates material from Chapters 1-3 |
|
3 F |
|||
|
6 M |
8-12 |
||
|
8 W |
Protein Function: Binding |
1, 3, 5-7. Chapter 5 Selected
Solutions |
|
|
10 F |
1-6, 9, 11, 13. Chapter 6 Selected
Solutions-Both Classes |
||
|
13 M |
12, 19. |
||
|
15 W |
15, 17- 20, 23, 27 Chapter 7 Selected
Solutions |
||
|
17 F |
EXAM 2 A through F in Pg6-116, G though Z in
RDB-1100 (Law College) |
50 points. Please bring: No 2. Pencils, Simple
Scientific Calculator+ Straight Edge (ruler), This exam integrates
material from Chapters 4, 5, 6 and 7. |
|
|
20 M |
|||
|
22 W |
5, 8, 10, 12-15 and another in the Solutions using
pBR322. |
||
|
24 F |
1, 2a, 2c,7-13, and 3 if you can cook. Chapter 10 Selected
Solutions |
||
|
27M |
|||
|
29W |
10-13, 15, 16, 19, 22 |
||
|
July |
|
|
|
|
1 F |
EXAM 3 A through F in Pg6-116, G
though Z in SIPA 125 |
50 points, integrates material from Chapter 3 and 6 into
Chapters 8, 10 and 11. Be sure to bring your calculator. |
|
|
4 M |
Independence Day HOLIDAY |
|
|
|
6 W |
1, 3, 4, 5, 7, 13 Chapter 12 Selected
Solutions-Both Classes |
||
|
8 F |
6, 9, 12, 14, 19-21, 24-27 Chapter 13 Selected
Solutions-Both Classes |
||
|
11M |
1, 2, 4-7, 9, 10, 14, 16 Chapter 14 Selected
Solutions-Both Classes |
||
|
13W |
21-24, 26, 27 |
||
|
15 F |
EXAM 4 A through F in Pg6-116, G
though Z in SIPA 125 |
|
50 points, bring your calculator. Integrates material from
Chapters 12, 13 and 14. |
|
18M |
1-9, 15, 18, 19, 30-32 Chapter 16 Selected
Solutions-Both Classes
Last Day to Drop. |
||
|
20W |
|||
|
22 F |
6 - 8, 10, 15, 16 |
||
|
25M |
1-4, 9, 10, 13, 16, 26, 28 Chapter 17 Selected
Solutions-Both Classes |
||
|
27W |
EXAM 5 A through F in Pg6-116, G
though Z in SIPA 125 |
|
50 points. Integrates material from Chapters 15, 16,
17 |
|
29 F |
1-5, 8, 11 Chapter 18 Selected
Solutions |
||
|
Aug |
|
|
|
|
1 M |
|
||
|
3 W |
6, 7, 9-11, 13, 14, 16, 18 Link to Malate-Aspartate
Shuttle Study Help |
||
|
5 F |
Final EXAM A
through F in Pg6-116, G though Z in SIPA 125 |
|
Comprehensive. 100
points. American Chemical Society Biochemistry Core Exam is 40
questions. |
Course Policies
1. Exams: There
will be six exams over the course of the semester - each worth 50 points plus
the cumulative Final Exam (100 points). There will be multiple
choice questions. There will be different FORMS of the Exam.
Wearing
brimmed hats or baseball caps during exams is not permitted, classroom lighting does not
require hats. Make-Up Exams will be given only to students
providing valid documentation of a medical or other serious problem. NO
EXAM IS DROPPED. All portions of the course are IMPORTANT. Answers
to the exams, grade distribution and Exam Wrapper will be sent by email to each
student in a timely fashion after the exams are graded.
2. Preparation for each
class: Study the Narrated Power Point well. Make sure you know all the material
before class. And, be able to do the selected End of Chapter Problems before
class.
3.Each class will have a
clicker graded activity = of 5 to 15 points. Missed class activities can
be made up with a written medical, legal
or other valid excuse within ONE WEEK of the missed class.
4. Final
Grade Calculation
|
Exams 1 through 6 and Final |
400 points |
|
iClicker Points |
200+ points |
|
TOTAL
POSSIBLE POINTS |
600+
points |
Class Clicker Points: at least
200, the class activities are constantly being improved and changed, the actual
number has come to a little more than 200. But is not the same from
semester to semester. They ALL get counted into your total-final points.
CONVERTING
POINTS TO LETTER GRADE OCCURS AT THE END OF THE SEMESTER: Total points
attained on all exams and classes are curved. If necessary the curve will
not allow the lowest C (passing for majors) to go below 50% of the total.
5.
Make-Ups (Classes and Exams), Extra Credit. If you miss a class
or exam, please contact the instructor within 24 hours of the exam or
class, if possible. .Missed classes and exams can be made up ONLY
if you have a valid written medical or legal excuse. Make-Up Exams
have no multiple choice questions. If you foresee that an unavoidable
prior commitment that will prevent you from attending an exam or class, contact
the instructor at least 2 days prior to the scheduled exam time to discuss
alternative = taking a make
up exam or making up class iClicker questions not more than ONE WEEK from the missed
exam or class.
There is NO EXTRA CREDIT, each student's grade comes exclusively from iClicker points, and exam points.
6.
Cheating
CHEATING WILL NOT BE TOLERATED!!!
Students caught cheating during an examination will be ejected from the exam
and given an "F" for the course.
USING
MORE THAN ONE CLICKER IN CLASS IS CHEATING
The FIU policy on incompletes is: An incomplete grade is a temporary symbol given at the discretion of the instructor for work not completed because of serious interruption not caused by the student's own negligence. An incomplete must be made up as quickly as possible but no later than two semesters or it will automatically default to the grade that the student earned in the course. There is no extension to the two semester deadline. The student must not register again for the course to make up the incomplete.
Incompletes will require written documentation (doctor's note, accident report, etc) of the underlying condition that impedes student progress. A form will need to be signed by the student detailing the procedure and agenda for completing course-work.
Students who receive an incomplete grade and have applied for graduation at the end of that term, must complete the incomplete grade by the end of the fourth week of the following term. Failure to do so will result in a cancellation of graduation. The student will need to reapply for graduation.